Denver Broncos at Indianapolis Colts

Quarterback Peyton Manning will return to Lucas Oil Dome for the second time since he joined the Broncos and will be looking for his first victory in his old house. The series between these two teams are tied with 12 wins apiece, but the Colts have won seven of the last eight. It will be the third meeting between Manning and Andrew Luck, and the former Stanford player has the advantage with two wins. Chuck Pagano’s team is favorite to win listed at the NFL betting Odds -1.0. The Colts are 4-1 SU and 5-0 ATS in the last five of the series. Denver has not won at Indianapolis since 2003.

Player to watch: Peyton Manning has seven touchdown passes and only one interception in the last three games against Indianapolis. It’s probable that for this match Manning could become or get very close to being the quarterback with the most passing yards in NFL history, surpassing Brett Favr